What'll get you a suspension (vs CPU):
1. QB - Throwing for >400 yards / >4 tds
2. RB - Rushing for >250 yards / >4 TDs with one player
3. WR/TE - Getting >200 yards / >3 TDs with one player
4. Defense (Can't put ceilings on this really, as it isn't really in your control -- as long as you aren't nanoing) (Just can't be outrageous sack numbers -- ex >5, etc.)
If it happens because of a supersim you are still at fault (that doesn't include a forced sim)
1st time penalty : 1 game suspension
2nd : 3 game suspension
3rd : 3 game suspension + all of your future CPU games will have CPU sliders set much tougher